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1

Assessing safety of extractables from materials and leachables in pharmaceuticals and biologics – Current challenges and approaches

Broschard, Thomas H., Glowienke, Susanne, Bruen, Uma S., Nagao, Lee M., Andrew Teasdale,, Stults, Cheryl L.M., Li, Kim L., Iciek, Laurie A., Erexson, Greg, Martin, Elizabeth A., Ball, Douglas J.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2016

Language:

english

File:

PDF, 578 KB

english, 2016

2

Characterization of new transgenic Big Blue® mouse and rat primary fibroblast cell strains for use in molecular toxicology studies

Gregory L. Erexson, David E. Watson, Kenneth R. Tindall

Journal:

Environmental and Molecular Mutagenesis

Year:

1999

Language:

english

File:

PDF, 62 KB

english, 1999

3

A modified mouse peripheral blood lymphocyte culture system for cytogenetic analysis

Gregory L. Erexson, Andrew D. Kligerman

Journal:

Environmental and Molecular Mutagenesis

Year:

1987

Language:

english

File:

PDF, 599 KB

english, 1987

4

Micronuclei in binucleated lymphocytes of mice following exposure to gamma radiation

Gregory L. Erexson, Andrew D. Kligerman, Edward C. Halperin, Gerard M. Honore, James W. Allen

Journal:

Environmental and Molecular Mutagenesis

Year:

1989

Language:

english

File:

PDF, 479 KB

english, 1989

5

The effects of acrylamide on mouse germ-line and somatic cell chromosomes

Dr. Lorraine C. Backer, Kerry L. Dearfield, Gregory L. Erexson, James A. Campbell, Barbara Westbrook-Collins, James W. Allen

Journal:

Environmental and Molecular Mutagenesis

Year:

1989

Language:

english

File:

PDF, 1.06 MB

english, 1989

6

Cytogenetic analyses of mice exposed to dichloromethane

James Allen, Andrew Kligerman, James Campbell, Barbara Westbrook-Collins, Gregory Erexson, Frank Kari, Errol Zeiger

Journal:

Environmental and Molecular Mutagenesis

Year:

1990

Language:

english

File:

PDF, 794 KB

english, 1990

7

Interspecies cytogenetic comparisons: Studies with x-radiation and bleomycin sulfate

Dr. Andrew D. Kligerman, Miriam F. Bryant, Carolyn L. Doerr, Edward C. Halperin, Puntipa Kwanyuen, Marc R. Sontag, Gregory L. Erexson

Journal:

Environmental and Molecular Mutagenesis

Year:

1992

Language:

english

File:

PDF, 745 KB

english, 1992

8

How to: Clinical cytogenetics “the act cytogenetics laboratory manual,” M. J. Barch (ed). New York, NY: Raven press, Inc., 1991, 625 pp, $120.00

Gregory L. Erexson

Journal:

Environmental and Molecular Mutagenesis

Year:

1992

Language:

english

File:

PDF, 98 KB

english, 1992

9

Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals

M. D. Shelby, G. L. Erexson, G. J. Hook, R. R. Tice

Journal:

Environmental and Molecular Mutagenesis

Year:

1993

Language:

english

File:

PDF, 1.52 MB

english, 1993

10

Cytogenetic effects of phosphine inhalation by rodents. I: Acute 6-hour exposure of mice

Dr. A. D. Kligerman, M. F. Bryant, C. L. Doerr, G. L. Erexson, P. Kwanyuen, J. K. McGee

Journal:

Environmental and Molecular Mutagenesis

Year:

1994

Language:

english

File:

PDF, 363 KB

english, 1994

11

cytogenetic and germ cell effects of phosphine inhalation by rodents: II. subacute exposures to rats and mice

Dr. A. D. Kligerman, J. B. Bishop, G. L. Erexson, H. C. Price, R. W. O'Connor, D. L. Morgan, E. Zeiger

Journal:

Environmental and Molecular Mutagenesis

Year:

1994

Language:

english

File:

PDF, 630 KB

english, 1994

12

Bleomycin sulfate-induced micronuclei in human, rat, and mouse peripheral blood lymphocytes

Gregory L Erexson, Miriam F. Bryant, Puntipa Kwanyuen, Andrew D. Kligerman

Journal:

Environmental and Molecular Mutagenesis

Year:

1995

Language:

english

File:

PDF, 546 KB

english, 1995

13

Characterization of a rat lymphocyte culture system for assessing sister chromatid exchange after in vivo exposure to genotoxic agents

A. D. Kligerman, J. L. Wilmer, G. L. Erexson

Journal:

Environmental and Molecular Mutagenesis

Year:

1981

Language:

english

File:

PDF, 764 KB

english, 1981

14

Characterization of a rat lymphocyte culture system for assessing sister chromatid exchange. II. Effects of 5-bromodeoxyuridine concentration, number of white blood cells in the inoculum, and inoculum volume

A. D. Kligerman, J. L. Wilmer, G. L. Erexson

Journal:

Environmental and Molecular Mutagenesis

Year:

1982

Language:

english

File:

PDF, 531 KB

english, 1982

15

Induction of cytogenetic damage in rodents after short-term inhalation of benzene

Gregory L. Erexson, James L. Wilmer, William H. Steinhagen, Andrew D. Kligerman

Journal:

Environmental and Molecular Mutagenesis

Year:

1986

Language:

english

File:

PDF, 698 KB

english, 1986

16

Sister chromatid exchange analysis in lung and peripheral blood lymphocytes of mice exposed to methyl isocyanate by inhalation

Dr. A. D. Kligerman, J. A. Campbell, G. L. Erexson, J. W. Allen, M. D. Shelby

Journal:

Environmental and Molecular Mutagenesis

Year:

1987

Language:

english

File:

PDF, 534 KB

english, 1987

17

Persistence of sce-inducing lesions in lymphocytes of mice exposed to diaziquone

A. D. Kligermana, M. F. Bryant, G. L. Erexson, J. R. Rabinowitz

Journal:

Environmental and Molecular Mutagenesis

Year:

1988

Language:

english

File:

PDF, 872 KB

english, 1988

18

Non-opsonising aggregates of IgG and complement in haemoglobin C erythrocytes

Nathaniel J. Brittain, Cindy Erexson, Lawrence Faucette, Jerrold Ward, Hisashi Fujioka, Thomas E. Wellems, Rick M. Fairhurst

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 879 KB

english, 2007

19

Plasmodium falciparum-infected erythrocytes induce tissue factor expression in endothelial cells and support the assembly of multimolecular coagulation complexes

I. M. B. FRANCISCHETTI, K. B. SEYDEL, R. Q. MONTEIRO, R. O. WHITTEN, C. R. EREXSON, A. L. L. NORONHA, G. R. OSTERA, S. B. KAMIZA, M. E. MOLYNEUX, J. M. WARD, T. E. TAYLOR

Journal:

Journal of Thrombosis and Haemostasis

Year:

2007

Language:

english

File:

PDF, 1.04 MB

english, 2007

20

Implications of an elevated sister-chromatid exchange frequency in rat lymphocytes cultured in the absence of erythrocytes

J.L. Wilmer, G.L. Erexson, A.D. Kligerman

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1983

Language:

english

File:

PDF, 956 KB

english, 1983

21

Analyses of sister-chromatid exchange and cell-cycle kinetics in mouse T- and B-lymphocytes from peripheral blood cultures

Gregory L. Erexson, James L. Wilmer, Andrew D. Kligerman

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1983

Language:

english

File:

PDF, 545 KB

english, 1983

22

Diaziquione-induced micronuclei in cytochalasin B-blocked mouse peripheral blood lymphocytes

Gregory L. Erexson, Andrew D. Kligerman, James W. Allen

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1987

Language:

english

File:

PDF, 489 KB

english, 1987

23

The induction of micronucleated polychromatic erythrocytes in mice using single and multiple treatments

R.R. Tice, G.L. Erexson, M.D. Shelby

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Year:

1990

Language:

english

File:

PDF, 417 KB

english, 1990

24

Induction of micronuclei by X-radiation in human, mouse and rat peripheral blood lymphocytes

Gregory L. Erexson, Andrew D. Kligerman, Miriam F. Bryant, Marc R. Sontag, Edward C. Halperin

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Year:

1991

Language:

english

File:

PDF, 427 KB

english, 1991

25

Cytogenetic studies of mice exposed to styrene by inhalation

A.D. Kligerman, J.W. Allen, M.F. Bryant, J.A. Campbell, B.W. Collins, C.L. Doerr, G.L. Erexson, P. Kwanyuen, D.L. Morgan

Journal:

Mutation Research/Environmental Mutagenesis and Related Subjects

Year:

1992

Language:

english

File:

PDF, 84 KB

english, 1992

26

Sister-chromatid exchange induction in peripheral blood lymphocytes of rats exposed to ethylene oxide by inhalation

A.D. Kligerman, G.L. Erexson, M.E. Phelps, J.L. Wilmer

Journal:

Mutation Research Letters

Year:

1983

Language:

english

File:

PDF, 396 KB

english, 1983

27

Reduction of diepoxybutane-induced sister chromatid exchanges by glutathione peroxidase and erythrocytes in transgenic Big Blue® mouse and rat fibroblasts

Gregory L Erexson, Kenneth R Tindall

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2000

Language:

english

File:

PDF, 84 KB

english, 2000

28

Application of simplified in vitro screening tests to detect genotoxicity of aristolochic acid

H. Zhang, M.A. Cifone, H. Murli, G.L. Erexson, M.S. Mecchi, T.E. Lawlor

Journal:

Food and Chemical Toxicology

Year:

2004

Language:

english

File:

PDF, 296 KB

english, 2004

29

Genotoxicity testing of a fenugreek extract

A.M. Flammang, M.A. Cifone, G.L. Erexson, L.F. Stankowski Jr.

Journal:

Food and Chemical Toxicology

Year:

2004

Language:

english

File:

PDF, 265 KB

english, 2004

30

Genotoxicity testing of a Salacia oblonga extract

A.M. Flammang, G.L. Erexson, M.S. Mecchi, H. Murli

Journal:

Food and Chemical Toxicology

Year:

2006

Language:

english

File:

PDF, 114 KB

english, 2006

31

Toxicological and cytogenetic assessment of a Salacia oblonga extract in a rat subchronic study

A.M. Flammang, G.L. Erexson, J.M. Mirwald, S.M. Henwood

Journal:

Food and Chemical Toxicology

Year:

2007

Language:

english

File:

PDF, 148 KB

english, 2007

32

Genotoxicity studies with pure trans-capsaicin

Sanjay Chanda, Greg Erexson, Colin Riach, Dawn Innes, Frances Stevenson, Hemalatha Murli, Keith Bley

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2004

Language:

english

File:

PDF, 125 KB

english, 2004

33

Lack of micronuclei formation in bone marrow of rats after repeated oral exposure to nickel sulfate hexahydrate

Adriana R. Oller, Greg Erexson

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2007

Language:

english

File:

PDF, 350 KB

english, 2007

34

Lack of in vivo clastogenic activity of grape seed and grape skin extracts in a mouse micronucleus assay

Journal:

Food and Chemical Toxicology

Year:

2003

Language:

english

File:

PDF, 91 KB

english, 2003

35

Micronuclei and gene mutations in transgenic Big Blue® mouse and rat fibroblasts after exposure to the epoxide metabolites of 1,3-butadiene

Gregory L Erexson, Kenneth R Tindall

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

36

Differential sensitivity of Chinese hamster V79 and Chinese hamster ovary (CHO) cells in the in vitro micronucleus screening assay

Gregory L. Erexson, M.V. Periago, Carol S. Spicer

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2001

Language:

english

File:

PDF, 72 KB

english, 2001

37

Genetic toxicity studies of 1,2,3,4-tetrahydro-9-acridinamine (tacrine)

Errol Zeiger, Gregory Erexson, Kristien Mortelmans, A Thilagar

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

1997

Language:

english

File:

PDF, 76 KB

english, 1997

38

An evaluation of the feasibility of using cytogenetic damage as a biomarker for alachlor exposure

Andrew D Kligerman, Gregory L Erexson

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

1999

Language:

english

File:

PDF, 80 KB

english, 1999

39

Comparison of sister-chromatid exchange frequencies in mouse T- and B-lymphocytes after exposure to 4-hydroxycyclophosphamide or phosphoramide mustard

Puntipa Kwanyuen, Gregory L. Erexson, Miriam F. Bryant, Andrew D. Kligerman

Journal:

Mutation Research Letters

Year:

1990

Language:

english

File:

PDF, 369 KB

english, 1990

40

Induction of sister-chromatid exchange (SCE) and cell-cycle inhibition in mouse peripheral blood B lymphocytes exposed to mutagenic carcinogens in vivo

A.D. Kligerman, G.L. Erexson, J.L. Wilmer

Journal:

Mutation Research/Genetic Toxicology

Year:

1985

Language:

english

File:

PDF, 582 KB

english, 1985

41

A comparison of sister-chromatid exchange in mouse peripheral blood lymphocytes exposed in vitro and in vivo to phosphoramide mustard and 4-hydroxycyclophosphamide

Miriam F. Bryant, Gregory L. Erexson, Andrew D. Kligerman

Journal:

Mutation Research/Genetic Toxicology

Year:

1989

Language:

english

File:

PDF, 499 KB

english, 1989

42

Cytogenetic studies of mice exposed to styrene by inhalation

A.D. Kligerman, J.W. Allen, M.F. Bryant, J.A. Campbell, B.W. Collins, C.L. Doerr, G.L. Erexson, P. Kwanyuen, D.L. Morgan

Journal:

Mutation Research/Genetic Toxicology

Year:

1992

Language:

english

File:

PDF, 686 KB

english, 1992

43

Analyses of cytogenetic damage in rodents following exposure to simulated groundwater contaminated with pesticides and a fertilizer

Andrew D Kligerman, Robert E Chapin, Gregory L Erexson, Dori R Germolec, Puntipa Kwanyuen, Raymond S.H Yang

Journal:

Mutation Research/Genetic Toxicology

Year:

1993

Language:

english

File:

PDF, 766 KB

english, 1993

44

Inhalation studies of the genotoxicity of trichloroethylene to rodents

A.D. Kligerman, M.F. Bryant, C.L. Doerr, G.L. Erexson, P.A. Evansky, P. Kwanyuen, J.K. McGee

Journal:

Mutation Research/Genetic Toxicology

Year:

1994

Language:

english

File:

PDF, 681 KB

english, 1994

45

Cytogenetic analyses of the in vitro and in vivo responses of murine cells to peroxyacetyl nitrate (PAN)

A.D. Kligerman, K. Mottus, G.L. Erexson

Journal:

Mutation Research/Genetic Toxicology

Year:

1995

Language:

english

File:

PDF, 605 KB

english, 1995

46

Association of Marginal Folate Depletion With Increased Human Chromosomal Damage In Vivo: Demonstration by Analysis of Micronucleated Erythrocytes

Everson, R. B., Wehr, C. M., Erexson, G. L, MacGregor, J. T.

Journal:

JNCI Journal of the National Cancer Institute

Year:

1988

Language:

english

File:

PDF, 1.60 MB

english, 1988

47

The Fifth Espen Congress

Kligerman, Andrew D., Moore, Martha M., Erexson, Gregory L., Brock, Karen H., Doerr, Carolyn L., Allen, James W., Nesnow, Stephen

Journal:

Clinical Nutrition

Year:

1983

Language:

english

File:

PDF, 66 KB

english, 1983

48

Genotoxicity studies of benz[l]aceanthrylene

Kligerman, Andrew D., Moore, Martha M., Erexson, Gregory L., Brock, Karen H., Doerr, Carolyn L., Allen, James W., Nesnow, Stephen

Journal:

Year:

1986

Language:

english

File:

PDF, 542 KB

english, 1986

49

Cytogenetic analysis of lymphocytes from rats following formaldehyde inhalation

Kligerman, A.D., Phelps, M.C., Erexson, G.L.

Journal:

Toxicology Letters

Year:

1984

Language:

english

File:

PDF, 396 KB

english, 1984

50

Analysis of cytogenetic damage in rat lymphocytes following in vivo exposure to nitrobenzene

Kligerman, A.D., Erexson, G.L., Wilmer, J.L., Phelps, M.C.

Journal:

Toxicology Letters

Year:

1983

Language:

english

File:

PDF, 500 KB

english, 1983